Identify Any Pathogen from Any Sample

Infectious diseases are one of the biggest killers in the world. Many infections are treatable if the pathogen can be quickly and accurately identified. IDbyDNA uses Next Generation Sequencing (NGS) based big data analytics to bring precision medicine to infectious diseases. IDbyDNA is on a mission to empower clinicians and researchers to identify any pathogen from any sample.

Taxonomer — The DNA Search Engine

Taxonomer is our breakthrough NGS-based metagenomic analysis technology. It dramatically improves the accuracy and speed of universal microorganism detection.

  • Peer-reviewed, best-in-class DNA search algorithm
  • Largest curated bacterial, viral and fungal databases for NGS data
  • Both nucleic acid and protein-based taxonomic classification for optimal sensitivity and specificity
  • Real-time big data analysis using an intuitive user interface
Taxonomer user interface

Publications

journal of infectious diseases

Robert Schlaberg, MD, MPH, Krista Queen, PhD, Keith Simmon, PhD, Keith Tardif, PhD, Chris Stockmann, PhD, MSc, Steven Flygare, PhD, Brett Kennedy, PhD, Karl Voelkerding, MD, Anna Bramley, PhD, Jing Zhang, PhD, Karen Eilbeck, PhD, Mark Yandell, PhD, Seema Jain, MD, MPH, Andrew T. Pavia, MD, Suxiang Tong, PhD, Krow Ampofo, MD

J. Infect. Dis. 2017 jix148. doi: 10.1093/infdis/jix148

CAP Archives of Pathology & Laboratory Medicine
Robert Schlaberg, MD, MPH; Charles Y. Chiu, MD, PhD; Steve Miller, MD, PhD; Gary W. Procop, MD; George Weinstock, PhD; the Professional Practice Committee and Committee on Laboratory Practices of the American Society for Microbiology; the Microbiology Resource Committee of the College of American Pathologists
Archives of Pathology & Laboratory Medicine, Early Online Release, doi: http://dx.doi.org/10.5858/arpa.2016-0539-RA 
new-england
Sankar Swaminathan, Robert Schlaberg, Julia Lewis, Kimberly E. Hanson, Marc R. Couturier
New England Journal of Medicine, DOI: 10.1056/NEJMc1610613
Genome Biology
Flygare S, Simmon KE, Miller C, Qiao Y, Kennedy B, Di Sera T, Graf EH, Tardif KD, Kapusta A, Rynearson S, Stockmann C, Queen K, Tong S, Voelkerding KV, Blaschke A, Byington CL, Jain S, Pavia A, Ampofo K, Eilbeck K, Marth G, Yandell M, Schlaberg R
Genome Biology 2016 17:111
Journal of Clinical Microbiology
Graf EH, Simmon KE, Tardif KD, Hymas W, Flygare S, Eilbeck K, Yandell M, Schlaberg R
J. Clin. Microbiol. 2016 vol. 54 no. 4

Recent News

May 12, 2017

Using the metagenomics analysis tool Taxonomer, researchers have been able to quickly tease out what pathogens are present in clinical and other samples. In addition, the Utah researchers, along with Arup Laboratories and IDbyDNA, have developed a Taxonomer-based clinical sequencing test to help diagnose respiratory disease.

April 21, 2017

“More effective pathogen identification will improve our understanding of pneumonia and guide treatment and site of care decisions.”

February 8, 2017

IDbyDNA makes the “Top 20 Disruptive Projects in Drug Development Data Analytics” as it brings Precision Medicine to Infectious Disease

January 2017

“In contrast to most of our current tests, you can use a metagenomic approach to find any and all potential pathogens in a patient sample without having to know what you’re looking for,” says Robert Schlaberg… “The advantage of a metagenomic approach is that you can start without having a hypothesis,” says Dr. Schlaberg, who spoke with CAP TODAY and presented in November at the Association for Molecular Pathology meeting on universal pathogen detection directly from specimens in the diagnostic laboratory. Another advantage of metagenomics is that it can detect bacteria, viruses, fungi, and parasites in one assay.

September 28, 2016

IDbyDNA, a precision medicine company focused on metagenomic approaches for infectious disease identification, today announced publication results in the New England Journal of Medicine that its metagenomics tool, Taxonomer, was used in the identification of Zika virus genomic sequence in the first Zika virus-related death in the continental U.S.

September 8, 2016

IDbyDNA, a precision medicine company focused on metagenomic approaches for infectious disease identification, announced today that it has closed $9 million in Series A financing. ARTIS Ventures led the round, with additional investments from ARUP Laboratories and other private investors. The funds will be used to further develop its Taxonomer-based DNA search technologies and to launch metagenomics-based clinical tests for infectious diseases.

July 15, 2016

When doctors take a sample of blood or a swab from someone’s throat, they may send it to a medical diagnostic lab like ARUP Laboratories. To determine certain diseases, scientists break open the cells, extract the DNA and RNA and sequence them, a technique used for genome sequencing, now used in diagnostic labs. A new web-based tool called Taxonomer is taking the mystery out of diagnosing illnesses. Powered by advanced computer software, doctors no longer have to suspect the cause of a patient’s infection.

June 6, 2016

Everyone has battled an infection. The culprits are pathogenic microbes such as bacteria, fungi, viruses and parasites. These pathogens can give us illnesses ranging from a nagging cold to a life-threating Staph infection. Infectious diseases claim many lives, but are often treatable if a rapid and accurate diagnosis is made.

June 6, 2016

Rapid identification of pathogens from patient samples is vital for the accurate diagnosis and treatment of infectious diseases. A new bioinformatics tool that analyses and visualizes metagenomics data promises to speed up this process to a matter of minutes.

May 26, 2016

Scientists from the University of Utah, ARUP Laboratories, and bioinformatics startup IDbyDNA have developed Taxonomer, a metagenomics analysis platform for universal pathogen detection and host-response profiling that they say is able to detect and classify pathogens more accurately, and in some cases more quickly, than some existing methods.

May 26, 2016

Scientists at the University of Utah, ARUP Laboratories, and IDbyDNA, Inc., have developed ultra-fast, meta-genomics analysis software called Taxonomer that dramatically improves the accuracy and speed of pathogen detection. In a paper published today in Genome Biology, the collaborators demonstrated the ability of Taxonomer to analyze the sequences of all nucleic acids in a clinical specimen (DNA and RNA) and to detect pathogens, as well as profile the patient’s gene expression, in a matter of minutes.

Founders

Guochun Liao, PhD, MBA

Founder, Chief Executive Officer

Former consulting professor at Stanford University, former VP Bioinformatics at Centrillion and former head of Computational Genomics at Roche Palo Alto

Robert Schlaberg, MD, Dr Med, MPH

Founder, Chief Medical Officer

Medical director at ARUP Laboratories and assistant professor of Pathology at the University of Utah

Mark Yandell, PhD

Founder, Chief Scientific Officer

Professor of Human Genetics and Edna Benning Presidential Endowed Chair at the University of Utah and co-director of the USTAR Center for Genetic Discovery

Martin Reese, PhD

Founder, Chairman

Founder, president and CSO of Omicia, and former founder and president of Neomorphic, one of the first Bioinformatics companies, which was sold to Affymetrix