Today’s Dilemma: Conventional pneumonia tests have limitations

The Solution: Explify Respiratory

Unlike conventional tests which only can detect a limited number of pathogens, Explify Respiratory applies an unbiased approach to finding any microorganism in a sample.

Applying metagenomic DNA and RNA sequencing enables Explify Respiratory to detect and identify bacterial, viral, fungal, and parasitic pathogens by their unique genome sequences. The shift from conventional testing for preselected pathogens to an unbiased metagenomic-based approach can help identify microorganisms that have previously been missed.

Testing can be performed on Bronchoalveolar Lavage (BAL), Sputum, Nasopharyngeal Swab and Tracheal Aspirate samples.

Explify Respiratory is useful for identifying:

  • Common and rare pathogens
  • Pathogens that are difficult to culture
  • New strains
  • Complex co-infections

Explify Respiratory provides physicians with answers even if they aren’t sure of what pathogens to test for. The test is also useful for immunocompromised patients and patients who previously tested negative with conventional tests.

1 The results of this clinical utility study were presented at the 2017 American Thoracic Society annual meeting in collaboration with The Children’s Hospital of Philadelphia

Explify Research applies metagenomic DNA and RNA sequencing to provide Clinical Researchers with comprehensive and advanced data analytics technology to accurately identify more than 50,000 microorganisms from any sample type.

Explify Research can associate findings to clinical phenotypes to aid researchers in understanding the role organisms identified may play in health and disease.

To learn more about collaborating with us on clinical research, contact us.

Explify Research Specimen (EXPRESS) Collection and Analysis Protocol

IDbyDNA created The EXPRESS Protocol, an IRB approved study designed to create a broad repository of multiple specimen types from patients with any infectious syndromes with matched analyzed metagenomic results. Specimens may include blood, plasma, serum, sputum, nasal swab, bronchoalveolar lavage (BAL), tracheal aspirate/secretion, pleural fluid, cerebrospinal fluid (CSF), synovial fluid, intraocular fluid, urine, fecal, or other bodily fluids/tissues such as those obtained during clinically indicated procedures (e.g., bronchoscopy, thoracentesis, or biopsy of an infection site).

If you are a researcher and interested in enrolling patients in EXPRESS, contact us here.